SI: Crime Scene Investigation is an innovative, fast-paced drama that follows a crew of forensic investigators as they solve crimes by analyzing evidence with advanced forensic tools.

The crew is headed by Gil Grissom (William Petersen), the senior investigator devoted to find the truth through the latest forensic methods combined with old-fashioned research and intuition. Alongside Gil is Catherine Willows (Marg Helgenberger), a single mother struggling to balance her home life with the rigors of her demanding job; Warrick Brown (Gary Dourdan), whose knowledge of the gambling world helps the Las Vegas based crew; Nick Stokes (George Eads), a self-proclaimed ladies man with an objective to find the wrong-doers; and Sara Sidle (Jorja Fox), the newest, outspoken member who often lets her troubled past get in the way of her job. The crew works along side Captain Jim Brass (Paul Guilfoyle), the former head of the graveyard shift turned captain; Greg Sanders (Eric Szmanda), a quirky lab tech working to be part of the CSI crew; and medical examiner Dr. Robbins (Robert David Hall).